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Volume 2, Issue 3, June 2014, Page: 38-41
Elevated Liver Enzymes in Patients with Cholecystitis
Amir A. Fikry, Department of Surgery, Faculty of Medicine, Mansoura University, Mansoura, Egypt
Arafat A. Kassem, Department of Internal Medicine, Faculty of Medicine, Al-Azhar University, Cairo, Egypt
Doaa Shahin, Department of Clinical Pathology, Faculty of Medicine, Mansoura University, Mansoura, Egypt
Hosam aldeen S. Shabana, Department of Internal Medicine, Faculty of Medicine, Al-Azhar University, Cairo, Egypt
Received: May 9, 2014;       Accepted: May 15, 2014;       Published: May 30, 2014
DOI: 10.11648/j.js.20140203.11      View  3475      Downloads  765
Abstract
Aims: To investigate changes in liver function tests in calcular cholecystitis (acute and chronic) and to relate that changes to cholecystitis. Methods: A retrospective study including 389 patients with clinical and sonographic evidence of cholecystitis with exclusion of other causes of elevated liver function tests, which are done preoperatively and four weeks postoperatively. Results: Increased liver function tests observed in both acute and chronic cholecystitis. The only significant differences between both groups were a higher bilirubin level (P= 0.001) and WBC (P= 0.018). Pre and post-cholecystectomy levels of AST, ALK-P and GGT were significantly changed (P= 0.001). Conclusion: Our study showed that the abnormal biochemical liver function tests resolved rapidly and spontaneously after cholecystectomy indicating transient hepatocellular injury with cholecystitis.
Keywords
Cholecystitis, Liver function tests, Leucocytosis
To cite this article
Amir A. Fikry, Arafat A. Kassem, Doaa Shahin, Hosam aldeen S. Shabana, Elevated Liver Enzymes in Patients with Cholecystitis, Journal of Surgery. Vol. 2, No. 3, 2014, pp. 38-41. doi: 10.11648/j.js.20140203.11
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